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Symbol
Name
ID
Lep
leptin
MGI:104663
Phenotype annotations related to reproductive system
Darker colors indicate more annotations
Human Phenotypes
Hypogonadism
Hypergonadotropic hypogonadism
Micropenis
Decreased testicular size
Hypoplasia of the ovary
Primary amenorrhea
Disease(s) Associated with LEP
congenital leptin deficiency

Mouse Phenotypes
decreased seminal vesicle weight
absent corpus luteum
decreased primary ovarian follicle number
decreased secondary ovarian follicle number
decreased testis weight
abnormal vagina orifice morphology
prolonged diestrus
prolonged estrus
prolonged estrous cycle
female infertility
infertility
male infertility
reduced male fertility
Availability Mouse Genotype
Lepm1Yst/Lepm1Yst
Lepob/Lepob
Leptm1.2Gvcao/Leptm1.2Gvcao
Leptm1b(EUCOMM)Hmgu/Leptm1b(EUCOMM)Hmgu
Leptm1.1Gvcao/Leptm1.1Gvcao
Tg(Adipoq-cre)1Evdr/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory